@article {7097,
	title = {Chiral electrochemical recognition by very thin molecularly imprinted sol-gel films},
	journal = {LangmuirLangmuir : the ACS journal of surfaces and colloids},
	volume = {21},
	number = {17},
	year = {2005},
	note = {MEDLINE AN 2005424800(Journal; Article; (JOURNAL ARTICLE); (RESEARCH SUPPORT, NON-U.S. GOV{\textquoteright}T))},
	month = {2005///},
	pages = {7842 - 7},
	abstract = {Thin films with enantioselective properties for electrochemically active chiral probes were developed. Enantioselectivity was accomplished via molecular imprinting. The films were fabricated through the sol-gel technique and were spin-coated on ITO electrodes. The chiral selectivity recognition was detected using two enantiomer pairs: D- and L-3,4-dihydroxyphenylalanine (D- and L-dopa) and (R)- and (S)-N,N{\textquoteright}-dimethylferrocenylethylamine [(R)-Fc and (S)-Fc]. A defined chiral cavity was obtained by selection of functional monomers that interact with the template molecule, followed by its removal. Chiral selection properties were measured by cyclic voltammetry and square wave voltammetry. For both template molecules, very good chiral recognition was revealed by electrochemical measurement. The nonspecific adsorption measured for reference nonimprinted films was negligible (less than 5\%). Dopa imprinted films revealed both high sensitivity, by the detection of 1 nM (0.2 ppb) concentration, and excellent selectivity, when challenged with a series of catechol derivatives. Fc-imprinted films were able to detect ca. 2 ppm of the target molecule, with very good enantioselectivity and low nonspecific adsorption. To our knowledge, this is the first report of successful molecular imprinting of a ferrocene derivative.[on SciFinder (R)]},
	isbn = {0743-7463},
	author = {Fireman-Shoresh, Sharon and Turyan, Iva and Mandler, Daniel and Avnir, David and Marx, Sharon}
}
