Electrochemically deposited poly(ethylene glycol)-based sol-gel thin films on stainless steel stents.

Citation:

Regina Okner, Domb, Abraham Jacob , and Mandler, Daniel. . 2009. “Electrochemically Deposited Poly(Ethylene Glycol)-Based Sol-Gel Thin Films On Stainless Steel Stents.”. New J. Chem.new Journal Of Chemistry, 33, Pp. 1596 - 1604.

Abstract:

Poly(ethylene glycol) (PEG) was modified with 3-isocyanatopropyltriethoxysilane (IPTS) to obtain PEG-disilane. This monomer was electrochem. polymd. and deposited onto a stainless steel surface to form a thin PEGylated sol-gel film. The monomer was characterized by 1H-NMR and FTIR spectroscopy. The sol-gel film was characterized by absorption-reflection IR spectroscopy (AR-FTIR), energy dispersive X-ray anal. (EDX), cyclic voltammetry (CV), profilometry, SEM and potentiodynamic polarization. AR-FTIR confirmed the formation of a polymer, while the stability of the polymeric film on stainless steel in buffer phosphate was studied by SEM. The polymer was successfully electrodeposited onto 316L coronary stents. Its flexibility was examd. by dilating the coated stents and inspecting it by SEM. The hydrophilic, smooth PEGylated sol-gel coating significantly reduced the activation and adhesion of platelets as compared with the bare stainless steel surface. This coating, which can be applied to complex geometries, such as stents, is likely to serve as an excellent biomaterial. [on SciFinder(R)]