Effect of Decorating Titanium with Different Self-Assembled Monolayers on the Electrodeposition of Calcium Phosphate.

Citation:

Noah Metoki, Mandler, Daniel , and Eliaz, Noam. . 2016. “Effect Of Decorating Titanium With Different Self-Assembled Monolayers On The Electrodeposition Of Calcium Phosphate.”. Cryst. Growth Des.crystal Growth & Design, 16, Pp. 2756 - 2764.

Abstract:

Calcium phosphate (CaP) ceramics are used in orthopedics and dentistry due to their excellent osseointegration and biocompatibility. The electrodeposition of CaP on titanium alloy covered with self-assembled monolayers (SAMs) was studied with respect to the influence of chain length, end-group charge, and anchoring group. SAMs with end-groups similar to the functional groups on the side chains of collagen were selected. This study is divided to three parts: (1) studying the effects of SAMs on the titanium substrate, (2) studying the process of nucleation and growth of the CaP on specific SAMs, and (3) characterizing the CaP coatings using various surface anal. techniques. It was concluded that the nucleation and growth behavior of CaP changed in the presence of the SAMs. Different surface energies and crystallog. phases were assocd. with this change. Although the nucleation remained progressive, the growth changed from three-dimensional on bare surfaces to two-dimensional on SAMs-covered surfaces. Moreover, the deposition kinetics was slower on SAMs-covered surfaces, with phases contg. a higher Ca/P ratio. Examn. of the coating revealed that different SAMs lead to different surface morphologies of the coating while maintaining its degree of crystallinity. Yet, the phase content changes from hydroxyapatite and octacalcium phosphate (HAp + OCP) on the bare electrode to OCP only on the SAMs-covered electrode. These changes may have a substantial effect on the in vivo behavior by changing the coating’s soly. and surface morphol., thus affecting cell adhesion, proliferation, and differentiation processes. [on SciFinder(R)]