Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode.

Citation:

Florina Teodorescu, Rolland, Laure , Ramarao, Viswanatha , Abderrahmani, Amar , Mandler, Daniel , Boukherroub, Rabah , and Szunerits, Sabine. . 2015. “Electrochemically Triggered Release Of Human Insulin From An Insulin-Impregnated Reduced Graphene Oxide Modified Electrode.”. Chem. Commun. (Cambridge, U. K.)Chemical Communications (Cambridge, United Kingdom), 51, Pp. 14167 - 14170.

Abstract:

An electrochem. insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 ± 4% of human insulin was released into a physiol. medium while preserving its biol. activity. [on SciFinder(R)]